Difference Between Scarlet Fever And Kawasaki Disease

Scarlet Fever and Kawasaki Disease are two distinct conditions that can often be confused due to some overlapping symptoms, especially in children. Both medical conditions demand timely diagnosis and treatment, but their causes, affected age groups, and treatment methodologies significantly differ. Scarlet Fever, caused by streptococcus bacteria, primarily affects children, presenting with a characteristic red rash. On the other hand, Kawasaki Disease, with its unknown cause, leads to blood vessel inflammation, affecting children under five years of age.

Scarlet Fever is a bacterial illness resulting in a fine, red rash and high fever, typically following a strep throat infection. Kawasaki Disease, however, is a more severe condition causing swollen blood vessels around the heart, with symptoms including fever, rash, and swollen glands, primarily affecting young children. The key to managing these conditions lies in early detection and appropriate treatment, differing vastly between the two: antibiotics for Scarlet Fever and immune therapy for Kawasaki Disease.

Understanding the differences between Scarlet Fever and Kawasaki Disease is crucial for parents and caregivers. While both can present with fever and rash, the nature of the rash, the age of the affected individual, and additional symptoms provide essential clues for accurate diagnosis. Timely medical intervention can prevent potential complications, underscoring the importance of distinguishing between these two conditions for the well-being of affected individuals.

Scarlet Fever Overview



Scarlet Fever is an infectious disease characterized by a bright red rash covering most of the body, sore throat, and high fever. It is caused by Group A streptococcus bacteria, which are also responsible for strep throat.


The primary cause of Scarlet Fever is the streptococcus bacteria. These bacteria release toxins that can lead to the distinctive rash associated with the illness. It’s most commonly spread through airborne droplets from an infected person’s coughs or sneezes.

ALSO READ:  What Is The Difference Between Cyruta And Cyruta Plus


Early Signs

The initial symptoms of Scarlet Fever include a sore throat, headache, fever, and swollen lymph nodes. These early signs usually develop two to four days after being infected.


As the disease progresses, patients notice a fine, red rash that feels like sandpaper. Starting typically on the chest and stomach, the rash spreads to other parts of the body. Other symptoms may include a red face but pale around the mouth, and a strawberry tongue.



Treatment for Scarlet Fever includes antibiotics to eradicate the bacteria. Penicillin or amoxicillin is commonly prescribed, and it’s crucial to complete the full course of antibiotics to prevent complications.

Home Care

In addition to medication, supportive home care measures include:

  • Staying hydrated
  • Resting
  • Using humidifiers to ease throat discomfort
  • Gargling with salt water for sore throat relief

Kawasaki Disease Overview



Kawasaki Disease is a rare condition that mainly affects children under five years old. It causes inflammation in the walls of some blood vessels in the body, particularly the coronary arteries which supply blood to the heart.


The exact cause of Kawasaki Disease is unknown. However, it does not seem to be contagious. It may be related to genetic factors, environmental triggers, and the body’s immune response to infections.


Early Signs

Early symptoms of Kawasaki Disease include a high fever that lasts for more than five days, red eyes without a thick discharge, a rash on the main part of the body and genital area, red, dry, cracked lips, and a swollen, red tongue (strawberry tongue).


If untreated, the disease progresses to later stages where symptoms might include peeling skin on the hands and feet, joint pain, diarrhea, vomiting, and abdominal pain. The most severe complications involve the heart and can lead to coronary artery aneurysms.



The main treatments for Kawasaki Disease include intravenous immunoglobulin (IVIG), a blood product that reduces inflammation of the blood vessels, and aspirin to lower fever, pain, and reduce the risk of blood clots.

Hospital Care

Children with Kawasaki Disease often need to be treated in a hospital to closely monitor their heart condition and response to treatment. The goal is to reduce inflammation and prevent heart damage.

Key Differences

Cause and Origin

  • Scarlet Fever: Caused by bacterial infection.
  • Kawasaki Disease: Cause is unknown.
ALSO READ:  Difference Between Unit Plan And Vs Lesson Plan

Age Group Affected

  • Scarlet Fever: Typically affects children aged 5-15 years.
  • Kawasaki Disease: Mainly affects children under five years old.

Symptoms Comparison

  • Unique Signs of Scarlet Fever: Sandpaper-like rash, strawberry tongue.
  • Unique Signs of Kawasaki Disease: Coronary artery inflammation, peeling skin on hands and feet.

Treatment Methods

  • Scarlet Fever: Treated with antibiotics.
  • Kawasaki Disease: Requires IVIG and aspirin, often in a hospital setting.

Diagnosis Challenges

Scarlet Fever

Common Misdiagnoses

Scarlet Fever can be easily confused with other childhood rashes, such as measles or fifth disease, due to its red rash and fever. Misdiagnosis can lead to unnecessary treatments or delay the correct one. Accurate diagnosis is typically achieved through a throat swab to detect Streptococcus bacteria, distinguishing it from viral causes of rash and fever.

Kawasaki Disease

Diagnostic Criteria

Diagnosing Kawasaki Disease is more challenging due to the lack of a single definitive test. Diagnosis relies on the presence of fever for five or more days along with at least four of the following symptoms: rash, conjunctivitis without pus, swollen extremities, red lips and tongue, swollen lymph nodes, and redness or swelling of the hands and feet. Early diagnosis is crucial to prevent heart complications, making awareness of these criteria vital for healthcare providers.

Complications and Risks

Scarlet Fever

Long-term Effects

Although rare with prompt treatment, untreated Scarlet Fever can lead to serious long-term complications, such as rheumatic fever, which can affect the heart, joints, nervous system, and skin. Other potential complications include kidney disease and ear infections. The importance of early treatment with antibiotics cannot be overstated to prevent these outcomes.

Kawasaki Disease

Heart Complications

The most serious risk of Kawasaki Disease is heart complications, including coronary artery aneurysms, myocarditis, and valvular heart disease. These can have lasting effects on a child’s health, sometimes requiring lifelong monitoring and treatment. Early administration of IVIG significantly reduces the risk of coronary artery aneurysms, highlighting the importance of prompt diagnosis and treatment.

Prevention Strategies

Scarlet Fever

Hygiene Practices

Preventing Scarlet Fever centers on good hygiene practices. Frequent hand washing, especially after coughing or sneezing and before eating, is crucial. Avoiding close contact with those infected and not sharing personal items like cups and utensils can also help reduce the spread of the bacteria causing Scarlet Fever.

ALSO READ:  Difference Between Carbonyl And Nitrosyl Complexes

Kawasaki Disease

Research and Limitations

Prevention strategies for Kawasaki Disease are more challenging due to its unknown cause. Current efforts focus on research to better understand the disease’s origins and develop prevention methods. Awareness among parents and healthcare providers about the signs and symptoms of Kawasaki Disease can aid in earlier diagnosis and treatment, potentially mitigating severe complications.

When to Seek Medical Help

Warning Signs for Immediate Attention

Knowing when to seek medical help is crucial for both Scarlet Fever and Kawasaki Disease. For Scarlet Fever, seek immediate medical attention if your child has a sore throat with a rash, high fever, or difficulty swallowing. For Kawasaki Disease, it’s critical to consult a doctor when a child has a fever lasting more than five days, especially if accompanied by other Kawasaki symptoms such as rash, eye redness, and swollen glands. Early intervention can prevent serious complications and ensure the best possible outcome for the child.


What causes Scarlet Fever and Kawasaki Disease?

Scarlet Fever is caused by an infection with group A Streptococcus bacteria, often following a sore throat or skin infection. Kawasaki Disease’s cause remains unknown, though it is believed to involve genetic, environmental, and infectious factors.

Can adults get Scarlet Fever or Kawasaki Disease?

While Scarlet Fever predominantly affects children, adults can also contract it, especially those in close contact with affected children. Kawasaki Disease is rare in adults, with the vast majority of cases occurring in children under five years old.

How are Scarlet Fever and Kawasaki Disease diagnosed?

Diagnosis of Scarlet Fever involves a physical exam, throat swab, and sometimes a blood test to confirm the presence of Streptococcus bacteria. Kawasaki Disease is diagnosed based on clinical symptoms and may require additional tests like echocardiography to assess heart involvement.

What are the complications of not treating these diseases?

Untreated Scarlet Fever can lead to serious complications such as rheumatic fever and kidney disease. Kawasaki Disease, if not treated promptly, can result in life-threatening heart issues, including coronary artery aneurysms.

Are there vaccines for Scarlet Fever and Kawasaki Disease?

Currently, there is no vaccine for either Scarlet Fever or Kawasaki Disease. Prevention focuses on good hygiene practices to avoid the spread of infections that could lead to Scarlet Fever and monitoring for early symptoms of Kawasaki Disease.


Distinguishing between Scarlet Fever and Kawasaki Disease is critical for ensuring the health and safety of affected individuals, particularly children. While both conditions share some symptoms, their causes, treatments, and potential complications vary significantly. Recognizing the differences can lead to prompt and appropriate medical care, preventing serious health issues.

The journey through understanding and managing these conditions underscores the importance of medical awareness and intervention. It highlights the need for attentive care and the crucial role of healthcare professionals in diagnosing and treating these distinct but similarly presenting diseases, safeguarding the well-being of our youngest population.

Leave a Comment